Editor-in-Chief, Robert Amdur, MD, discusses two papers published in PRO related to the question of using a vaginal dilator during radio-chemotherapy for carcinoma of the anus: "Daily Vaginal Dilator Use During Radiation for Women With Squamous Cell Carcinoma of the Anus: Vaginal Wall Dosimetry and Patient-Reported Sexual Function" (2024, Volume 14, Issue 2, PMID 37898354) and "ECOG-ACRIN Guideline for Contouring and Treatment of Early Stage Anal Cancer Using IMRT/IGRT" (2022, Volume 12, Issue 4, PMID 35717050).