In this episode, Rachel Cole, PharmD, walks us through the evolving landscape of restless leg syndrome management, highlighting why dopamine agonists are no longer first-line therapy and what that means for clinical practice. 

You’ll learn about the importance of checking for iron deficiency, practical non-drug interventions, and alternative medications like gabapentin and pregabalin. 

Rachel shares actionable tips for educating patients, managing tricky cases, and staying up to date with the latest sleep medicine guidelines, so you can take confident steps forward in caring for patients with RLS.

This is an excerpt from our July 2025 Pharmacy Essential Updates continuing education webinar series.

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CE Information:

TRC Healthcare offers CE credit for this podcast for pharmacist subscribers at our platinum level or higher and pharmacy technician subscribers. Log in to your Pharmacist’s Letter or Pharmacy Technician’s Letter account and look for the title of this podcast in the list of available CE courses. None of the speakers have anything to disclose.

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Clinical Resources from Pharmacist’s Letter, Pharmacy Technician’s Letter, and Prescriber Insights: 

• Article: Stay in Step With Treatments for Restless Legs Syndrome
• Chart: Oral Iron Comparison and Practical Considerations for Use

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