After nearly a decade at Index Ventures, where he backed standout fintech companies like Plaid, Persona, Lithic, and Pilot, Mark Goldberg left to launch Chemistry, an early-stage venture firm.

Founded alongside Kristina Shen and Ethan Kurzweil, the $350 million fund is part of a growing trend in venture capital: seasoned investors breaking out from large platforms to build more focused, boutique outfits.

Today on Equity, Mary Ann Azevedo caught up with Goldberg about what led him to make the move, what Chemistry is all about, and how the venture landscape has evolved over the past few years.

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Equity is TechCrunch’s flagship podcast, produced by Theresa Loconsolo, and posts every Wednesday and Friday. 

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