Clinical Capsules

What’s New in Acute Sinusitis: Antibiotics vs. Watchful Waiting


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Think every sinus infection needs an antibiotic? Think again.

Updated guidelines for acute bacterial rhinosinusitis are sparking discussions about when antibiotics are truly warranted—and pharmacy teams play a key role in helping guide practice. 

In this episode, TRC Healthcare Assistant Editor and Clinical Pharmacist Gina Corley, PharmD, explains new recommendations for “watchful waiting,” when to initiate antibiotics, supportive care measures to try, and more.

You’ll also hear practical pearls on first-line therapy, dosing strategies for amoxicillin and amoxicillin/clavulanate, and safe alternatives for penicillin-allergic patients. Plus, Gina shares tips for counseling patients and reducing antibiotic resistance while improving outcomes.

This is an excerpt from our December 2025 Pharmacy Essential Updates continuing education webinar series.

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CE Information:

TRC Healthcare offers CE credit for this podcast for pharmacist subscribers at our platinum level or higher and pharmacy technician subscribers. Log in to your Pharmacist’s Letter or Pharmacy Technician’s Letter account and look for the title of this podcast in the list of available CE courses. None of the speakers have anything to disclose.

Claim Credit

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Clinical Resources from Pharmacist’s Letter, Pharmacy Technician’s Letter, and Prescriber Insights

  • Article: Keep A “Watch and Wait” Approach for Acute Sinusitis
  • Chart: Managing Beta-Lactam Allergies
  • Chart: Antibiotic Therapy: When Are Shorter Courses Better?

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