In total, Lilly has committed to investing more than $13 billion in its facilities and activities at the district. It has revealed its plans over four announcements in the last two and a half years, with the most recent coming earlier this month: a $4.5 billion project called the Lilly Medicine Foundry. Where the previous investments were all about manufacturing, this latest announcement is more about research. The so-called foundry will focus on how to make new medicines better and faster, while also increasing capacity for clinical trial medicines. Other potential payoffs for Hoosiers include creating an anticipated 400 full-time jobs for highly skilled workers, who will include engineers, scientists and operations personnel.

In this week’s edition of the IBJ Podcast, reporter John Russell puts it all in context and explores in greater depth the potential impact of the foundry as Lilly hovers near a milestone that would make it one of the most valuable companies in America.