Introducing Could Miami/Mario Cristobal be on UPSET ALERT at Cal? Week 6 ACC/Big 12 picks from Locked On College Football.

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ESPN's College GameDay is heading to Berkeley, CA for the first time EVER as Miami travels across the country to take on Cal. How do the Bears pull the upset and propel themselves towards the top of the ACC?

On today's episode of Locked On College Football, Spencer McLaughlin goes through and makes his picks for every Week 6 game in the ACC aside from the GameDay matchup in Berkeley. Louisville hosting SMU could later decide if one of those teams will make the ACC Championship game.

The Big 12 doesn't have a high profile matchup this week, but Arizona has a chance to prove something at home against a hot Texas Tech team. Will Arizona State continue Kansas' slide in Tempe?

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