Nearly 9 percent of Native Americans experienced a major depressive episode according to the 2013 National Survey on Drug Use and Health: Mental Health Findings. That means they experienced severe problems with sleep, eating, energy, concentration, and self-worth—enough to interfere with their daily lives. The survey lists Native Americans as the group with the highest rate of depression. We talk to experts about the signs and treatments for depression and some of the suspected causes for the illness in Native populations.