AbbVie's Humira dam is beginning to crack. Crain’s health care reporter Katherine Davis talks with host Amy Guth about how the tide appears to be turning as CVS' pharmacy benefit manager replaces the blockbuster drug on its formulary list.

Plus: City Council greenlights Johnson's plan to pump $1.25 billion into housing and development, ShipBob picks JPMorgan to lead IPO, ex-Citadel exec's trading firm expanding and moving to revamped Loop tower, and how Chicago's venture-capital and startup scene stacks up globally.