Home prices here just keep climbing. Crain’s residential real estate reporter Dennis Rodkin shares key takeaways from the latest data with host Amy Guth.

Plus: Insights from the Trump administration’s spending freeze and subsequent reversal from Crain’s reporter John Pletz, Advocate to close 55 clinics inside Walgreens, investors buy Wacker Drive office tower with plan for $30 million renovation and White House offers buyouts to federal employees resisting in-person work.

Planned Parenthood of Illinois is closing four clinics due to a financial shortfall stemming from rising patient volume and growing health care costs. Crain’s health care reporter Katherine Davis discusses with host Amy Guth.

Plus: Crypto is shedding its stigma under Trump — and Chicago firms are ready; Gap plans State Street factory store; Radio Flyer closes Woodfield Mall store, its only brick-and-mortar location; and Ken Griffin taps Related to develop new Miami HQ.

The U.S. surgeon general advised earlier this month that alcohol is a leading preventable cause of cancer, presenting alcoholic beverage makers with a new hurdle. Crain's consumer products reporter Ally Marotti discusses with host Amy Guth.

Plus: Pritzker, Johnson, Emanuel blast Trump on DEI, immigration orders; Chicago schools to take $400M advance from revolving credit; AbbVie makes cancer and immunology pact with Neomorph; and former Groupon HQ sells for 83% less than 2018 price.

Crain’s residential real estate reporter Dennis Rodkin talks with host Amy Guth about news from the local housing market, including the Chicago real estate brokers and landlords accused of discriminating against housing voucher holders.

Plus: Stellantis commits to restarting Belvidere and rehiring 1,500 workers, Allstate files for rate hike of 14.3% for Illinois homeowners, United sees profit rebound as airlines buck winter doldrums and suburban office vacancy begins the year at record-high 32%.

Chicago's efforts to fight opioid overdoses show early promise. Crain’s health care reporter Katherine Davis discusses with host Amy Guth.

Plus: Gov. JB Pritzker says feds targeting 2,000 in Chicago for deportation as the threat of immigration raids stifles Little Village commerce, United Center owners snap up nearby lots as Near West Side mega-project takes shape, Pulaski Savings Bank closed by regulators due to "unsound" condition and proposed zoning changes could bring more density to Far North Side corridor.

Who’s who in Chicago? Crain’s editor Ann Dwyer talks with host Amy Guth about the list of local power players and how the latest rendition came together.

Plus: Northwestern posts surplus and near-record fundraising, Goose Island development site hits the market, investor pays $40 million for Lakeview apartments, FDA details unsanitary conditions at facility linked to McDonald's E. coli outbreak and mask rules are back at hospitals as respiratory illnesses climb.

Crain’s residential real estate reporter Dennis Rodkin joins host Amy Guth to talk news from the local market, including the owner of Michael Jordan’s former home selling $1 million ownership shares, Mike Ditka landing a buyer for his Florida home as he moves back to Chicago and more.

Plus: RTA pitches Springfield on $1.5 billion revamp to save and even enhance service; S&P downgrades Chicago's credit rating, with pushback from the mayor; Walgreens closing five stores across South, West sides and the company’s CEO says its anti-shoplifting effort is hurting sales; and United Center owners reveal new details of planned 1901 Project.

Dr. Ngozi Ezike, the face of Illinois' response to the COVID-19 pandemic, admitted to an ethics violation for taking the CEO job at Sinai Chicago and will pay a $150,000 fine. Crain’s health care reporter Katherine Davis discusses with host Amy Guth.

Plus: Startup investments still sluggish in Chicago, Publicis Groupe merges Leo Burnett and Publicis Worldwide to form new creative unit, NASCAR quietly lost a massive local sponsor of its Chicago race and Illinois attorney general pushes back on Walmart's plans to roll back DEI programs.

Crain's cannabis reporter John Pletz talks with host Amy Guth about the hemp industry after a bill aimed at regulating it died in Springfield, dealing a political blow to Gov. JB Pritzker.

Plus: CTA chief Dorval Carter is stepping down, City Council vote planned to lower Chicago speed limit from 30 mph to 25 mph, new bill calls on U of I system to divest from fossil fuels and downtown office landlords start 2025 with new record-high vacancy.