Dr. Diogo Barardo, Director of Research and Development at Novos, joins Buck to discuss Novos' innovative approach to longevity supplements, unpacking the differences between biological and epigenetic aging and the impact of the Drug Age database. He details how Novos evaluates compounds for safety and efficacy, the unique ingredients in their flagship NovoScore, and the promising roles of lithium microdoses and NAD precursors. Their conversation also delves into the latest in longevity science, from the controversies around resveratrol to mitophagy's role in cellular health, the complexities of supplement dosages, and the potential of aging biomarkers and AI-driven research for consumer longevity solutions.

Learn more about Dr. Barardo and NOVOS: https://novoslabs.com/

00:00 Introduction to Longevity Research and Novos 02:04 Understanding Biological and Epigenetic Aging 09:20 The Drug Age Database and Its Significance 10:37 Longevity Compounds and Their Efficacy 20:58 The Role of Lithium and NAD Precursors 26:44 The Role of Mitochondria in Aging 36:14 Leveraging AI in Longevity Research