In this is a two part episode Buck talks with Dr. Michael Mantz, MD about Ketamine and Psychedlics. Part 2 will be online for our regular Wednesday episode drop.

• 0:00:39 - About Dr. Michael Mantz
• 0:02:47 - Studying With Famous Herbalists In Utah
• 0:06:46 - Dr. Mantz's Integrative Approach Combining Nutrition, Exercise And Supplements
• 0:08:21 - Dr. Mantz's Current Practice: The Santa Barbara Integrative Medicine
• 0:08:43 - Ketamine Assisted Psychotherapy
• 0:11:06 - What Are Psychedelics?
• 0:12:49 - Understanding Ketamine's Mechanism
• 00:14:47 - Ketamine As A Dissociative Anesthetic
• 00:16:38 - Effects Of Ketamine On GABA
• 0:17:53 - Ketamine Working On The Nmda Receptors
• 0:19:44 - NMDA Receptors And Expanding Consciousness
• 0:22:23 - Augmenting Psychotherapy With Ketamine
• 0:28:37 - Placebo Effect And Inflection Points
• 0:33:35 - Clinical Depression And Its Symptoms
• 0:35:18 - SIG-E-CAPS And Dysregulations Of Sleep
• 0:37:24 - Is Depression Physiological Or Psychological?
• 0:39:56 - The Impact Of Depression On Perception
• 0:40:10 - Understanding Depression And Medication Options
• 0:47:39 - Effectiveness Of SSRIS In Treatment
• 0:52:38 - Ketamine Therapy And Treating Depression
• 0:54:44 - Western Medicine's Relationship With Psychedelics
• 1:01:55 - Today's Opioid Epidemic
• 1:04:26 - Psychedelics In Mental Health