What does it mean to live well in a world where nothing is certain — not in medicine, not in life? In this episode, we follow a high school teacher who asks his students to examine “the good life” through philosophy, Buddhism, and existential inquiry. We meet two women — a Buddhist monk and a disability rights advocate — who bring spiritual wisdom to the messy realities of illness, caregiving, and embodiment. Their stories, woven with reflections on impermanence, suffering, and compassion, offer a new way of thinking about uncertainty: not as something to fix, but as something to live with.

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The "Uncertainty in Medicine" series is generously funded by the ABIM Foundation, by the Josiah Macy Jr. Foundation, and the Gordon & Betty Moore Foundation.

The Nocturnists is supported by The California Medical Association and donations from listeners like you.

Host: Emily Silverman, MD

Uncertainty Correspondent: Alexa Miller

Series Illustrations by Eleni Debo