Core IM | Internal Medicine Podcast

#136 How Did Diabetes Medications Become Obesity Meds? Beyond Journal Club on SURMOUNT-1 Trial


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What is the difference between semaglutide (ozempic) and tirzepatide (mounjaro) in outcomes and mechanism? How did we find out diabetes medications can help with weight loss?

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Show Notes & Transcript

  • 02:08 Framework for thinking about obesity
  • 03:42 History of obesity treatment
  • 06:29 Gila monsters and GLP and GIP mechanisms
  • 08:29 Story of how medications for diabetes were found to have a weight loss benefit
  • 12:50 SURMOUNT-1 trial


Tags: IMCore, CoreIM, primary care, cardiology, nurse practitioner, pharmacist, physician assistant



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