The Glucose Never Lies® Podcast

15: C-Peptide - What type of type 1 diabetes do you have?


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Hosted by diabetes dietitian John Pemberton, this show blends science and real-life experience to make managing type 1 diabetes easier, clearer, and more human. Smart insights, practical tips, and honest conversations await. 

It's all about C-Peptide and what it means for people living with T1D! 

 
🕒 [00:09] Think all T1D is the same? Think again.

🕒 [02:14] Some people really do have it harder — and “brittle diabetes” might be real.

🕒 [04:37] Enter C-peptide: a marker of how much insulin your body still makes.

🕒 [06:10] Know your number:
• High: >200 pmol/L
• Intermediate: 30–200
• Low: <30

🕒 [09:11] Diagnosed young? You likely have lower C-peptide. John, diagnosed at 27, still has 220 after 10 years.

🕒 [10:20] High C-peptide = better time-in-range, fewer hypos, fewer complications.

🕒 [13:10] Why? More portal insulin + less glucagon = smoother control.

🕒 [14:01] Use your C-peptide to prioritise tech and tailor therapy (GLP-1s, HCL systems, nutrition).

🕒 [17:55] Most of all—be kind to yourself. It’s not weakness. It’s biology.
 
 

Key resources 

Episode 14: Insulin Resistance and T1D

C-Peptide full article – click here 


 

For collaboration, partnerships, or press enquiries: John Pemberton — [email protected]

For creative, social, and production enquiries: Anjanee Kohli[email protected]

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