Raphael Bousso is the Chancellor’s Chair in Physics at the Berkeley Center for Theoretical Physics, where he leads the Bousso Group in research on quantum gravity and quantum information. He is a renowned string theorist famous also for his development of the string theoretic landscape and the Bousso bound in holography. In this episode, Robinson and Raphael talk about the foundations of quantum mechanics and whether or not there are any deep mysteries within the theory that remain to be solved, and whether philosophical discussion of these issues is overblown. More particularly, they get into what quantum theories tell us about the world, whether we need different interpretations of quantum mechanics, whether the final theory of the universe will be quantum mechanical, how quantum mechanics connects to cosmology, the multiverse, and quantum gravity, and more.