More at http://philosophytalk.org/shows/transformative-experiences.

We are faced with decisions all the time in life. Normally, we think about the possible outcomes and chose a course of action that matches what we take to be of most value to us. However, one might think that some decisions—like whether or not to have a child—can so profoundly transform our lives that we cannot possibly know what the outcome will be like until it actually happens. Are these the kind of decisions in which our regular approach to decision-making becomes useless? Can life-changing decisions ever be made rationally? If not, can we still make good choices? John and Ken make some major decisions with Laurie Paul from UNC Chapel Hill, author of "Transformative Experience."