The Curbsiders Internal Medicine Podcast

#498 Opioid Withdrawal with Dr. Ashish Thakrar


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Grow your management tools for opioid withdrawal in the hospital. Investigate how to decide between methadone and buprenorphine, additional medications to manage symptoms and how and when to use short-acting opioids for management of withdrawal. We’re joined by Ashish Thakrar, MD at the University of Pennsylvania. 

Claim CME for this episode at curbsiders.vcuhealth.org!
By listening to this episode and completing CME, this can be used to count towards the new DEA 8-hr requirement on substance use disorders education.

Episodes | Subscribe | Spotify | iTunes | [email protected] | CME!


Show Segments

  • Intro, disclaimer, guest bio
  • Guest one-liner
  • Case from Kashlak; Definitions
  • Symptoms of opioid withdrawal
  • Medications for the management of opioid withdrawal
  • Buprenorphine precipitated withdrawal
  • Starting Buprenorphine: Experiences and Strategies 
  • Titrating Methadone: Dosage and Adjuncts
  • Adjunctive short-acting opioids
  • Emerging Trends in Drug Supply: Xylazine and Medetomidine
  • Outro 

  • Credits

    • Producer, Show Notes: Zina Huxley-Reicher
    • Infographics: Zina Huxley-Reicher MD and Zoya Surani
    • Hosts: Carolyn Chan, MD MHS, Zina Huxley-Reicher MD, Shawn Cohen, MD
    • Reviewer: Payel Jhoom Roy, MD, MSc
    • Showrunner: Carolyn Chan, MD, MHS
    • Technical Production: PodPaste
    • Guest: Ashish Thakrar, MD MHSP

    • Sponsor: Mint Mobile 

      Shop plans at MINTMOBILE.com/CURB

      Sponsor: Freed

      Use code: CURB50 to get $50 off your first month when you subscribe!

      Sponsor: FIGS 

      We’ve teamed up with FIGS, and now Curbsiders listeners can get 15% off. Just go to WearFIGS.com and use code FIGSRX.



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