In this episode we explore a very rare, but devastating disease called primary hyperoxaluria, which usually destroys the kidneys when patients are still very young and afterwards, the calcium oxalate crystals deposit in the bones, joints, vessel walls, the heart and other organs, leading to a dramatic shortening of life. Effectively the patient is slowly turning into stone. Justine Bacchetta, a world-renowned expert, will help us understand this disease and navigate the new and very effective therapies that have recently become available.