December 12, 2023

59: Navigating the Complex World of AGEs: Unraveling the Impact of Advanced Glycation End Products on our Health | Part One

47 minutes

In this episode, we delve into the multifaceted world of Advanced Glycation End Products (AGEs), starting with a comprehensive overview of what they are and their pivotal role in human health. We'll explore the intricate process behind AGE formation within the body, shedding light on the factors that contribute to its creation. A major focus will be on unraveling the significant impact of AGEs on the body, drawing connections between these compounds and the aging process, as well as their involvement in various chronic diseases. Our exploration extends further into lifestyle factors that play a role in the formation of AGEs, unveiling how certain habits and environmental aspects contribute to their accumulation. We address diagnostic methods utilized in monitoring AGE levels, discussing various biomarkers and testing techniques crucial for early detection and intervention.

Next week, we'll dissect the crucial link between diet choices and the buildup of AGEs, illuminating the role of specific foods and cooking methods in this process. We will identify high-AGE foods and cooking methods notorious for elevating AGE levels. To conclude, the series will provide practical tips and tricks aimed at minimizing exposure to AGEs, offering actionable advice to reduce their impact on overall health and well-being.

Outline:

- Advanced Glycation End Products (AGEs) and their significance in human health.

- Understanding AGEs: Insights into how AGEs are formed in the body.

- Impact on the body: Relationship between AGEs and aging, and chronic diseases such as diabetes, neurodegenerative disorders, and cardiovascular diseases, among others.

- Lifestyle factors contributing to AGE formation.

- Role of diet in AGE accumulation.

- Diagnostic methods and monitoring AGE levels: Discussion of biomarkers, testing techniques, and the importance of early detection and intervention.

- Identification of high-AGE foods and cooking methods that increase AGE levels. Conclusion with tips and tricks to reduce exposure to AGES.

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Interesting Articles:

https://www.nature.com/articles/s42003-021-01909-5

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3951818/

https://www.nature.com/articles/s12276-021-00561-7

https://www.sciencedirect.com/science/article/abs/pii/S0165017302002734?via%3Dihub

https://www.mdpi.com/1422-0067/18/2/421

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8810476/

https://pubmed.ncbi.nlm.nih.gov/34155155/

https://pubmed.ncbi.nlm.nih.gov/26626334/

https://www.mdpi.com/2072-6643/2/12/1247

https://pubmed.ncbi.nlm.nih.gov/36040219/

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4571620/

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By Tara Quintana

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