Welcome to the NeurologyLive® Mind Moments® podcast. Tune in to hear leaders in neurology sound off on topics that impact your clinical practice.

In this episode, we spoke with Robert Zivadinov, MD, PhD, director of the Buffalo Neuroimaging Analysis Center, and a professor of neurology and biomedical informatics at the Jacobs School of Medicine & Biomedical Sciences at the University at Buffalo. He discussed the recent CASA-MS study that he and colleagues conducted into a subgroup of patients with multiple sclerosis (MS) who develop rapid and progressive disability at a relatively young age, which he presented earlier this year at the 2023 Americas Committee for Treatment and Research in MS Forum, and the critical effectively need to treat this group of patients. The study was carried out at The Boston Home, a specialized residential facility for individuals with advanced progressive neurological disorders, in Dorchester, Massachusetts, and at the University at Buffalo, in New York.

Episode Breakdown:

1:10 – Background on the CASA-MS study subpopulation

3:45 – Topline results of the study

6:05 – The need for further clarification in MS populations

7:10 – The utility of biomarkers such as GFAP

12:15 – Further assessment plans for the CASA-MS cohort

14:15 – Neurology News Minute

18:35 – Access to the tools to characterize progressive MS

21:30 – The potential with portable MRI and artificial intelligence

25:25 – Unmet needs in progressive MS

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The stories featured in this week's Neurology News Minute, which will give you quick updates on the following developments in neurology, are further detailed here:

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REFERENCE

1. Zivadinov R, Jakimovski D, Burnham A, et al. Comprehensive Assessment of Severely Affected Multiple Sclerosis (CASA-MS) Study. Presented at: ACTRIMS Forum; February 25-28, 2023; San Diego, CA. P430. www.abstractsonline.com/pp8/#!/10822/presentation/468