Welcome to the NeurologyLive® Mind Moments® podcast. Tune in to hear leaders in neurology sound off on topics that impact your clinical practice.

In this episode, Thomas Crawford, MD, a pediatric neurologist at Johns Hopkins Medicine, spoke on the recently published 5-year analysis of the NURTURE study (NCT02386553), a long-term trial assessing the efficacy and safety of nusinersen (Spinraza; Biogen) in presymptomatic infants with spinal muscular atrophy (SMA). Crawford discussed the significance of the positive findings, the shift in conversations around treatment optimization in SMA, and how subgroup data may factor into the design of future trials.

Episode Breakdown:

1:20 – Benefits seen with nusinersen in NURTURE 

4:10 – Changes in goals for treating SMA

6:05 – Complexities with getting infants therapy days after diagnosis

9:40 – Neurology News Minute

12:30 – Subgroup findings from NURTURE

15:20 – Ways to improve treatment optimization in SMA

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The stories featured in this week's Neurology News Minute, which will give you quick updates on the following developments in neurology, are further detailed here:

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