
Sign up to save your podcasts
Or


It’s common knowledge that many diseases and conditions have some kind of genetic link. But that wasn't always the case. In 1990, long before the Human Genome Project tied so many health issues to differences in genetics, researchers identified a gene called BRCA1. It was the first gene linked to a hereditary form of any common cancer. People with certain variants of BRCA1 stood a higher risk of developing breast and ovarian cancer than those without those mutations.
Geneticist Mary-Claire King and her lab were the first to identify that gene. She joined Host Flora Lichtman in September 2025 to talk about her background, her research, and her approach to science.
Guest:
Dr. Mary-Claire King is an American Cancer Society Professor in the departments of Genome Sciences and Medicine at the University of Washington in Seattle.
Other episodes you may enjoy:
Transcripts for each episode are available within 1-3 days at sciencefriday.com.
Subscribe to this podcast. Follow our show on Instagram, TikTok, Facebook, and Bluesky @scifri and sign up for our newsletters. Got a science question that’s keeping you up at night? Call us: 877-472-4374
Hosted by Simplecast, an AdsWizz company. See pcm.adswizz.com for information about our collection and use of personal data for advertising.
By Science Friday and WNYC Studios4.4
60206,020 ratings
It’s common knowledge that many diseases and conditions have some kind of genetic link. But that wasn't always the case. In 1990, long before the Human Genome Project tied so many health issues to differences in genetics, researchers identified a gene called BRCA1. It was the first gene linked to a hereditary form of any common cancer. People with certain variants of BRCA1 stood a higher risk of developing breast and ovarian cancer than those without those mutations.
Geneticist Mary-Claire King and her lab were the first to identify that gene. She joined Host Flora Lichtman in September 2025 to talk about her background, her research, and her approach to science.
Guest:
Dr. Mary-Claire King is an American Cancer Society Professor in the departments of Genome Sciences and Medicine at the University of Washington in Seattle.
Other episodes you may enjoy:
Transcripts for each episode are available within 1-3 days at sciencefriday.com.
Subscribe to this podcast. Follow our show on Instagram, TikTok, Facebook, and Bluesky @scifri and sign up for our newsletters. Got a science question that’s keeping you up at night? Call us: 877-472-4374
Hosted by Simplecast, an AdsWizz company. See pcm.adswizz.com for information about our collection and use of personal data for advertising.

91,297 Listeners

21,954 Listeners

43,837 Listeners

32,246 Listeners

38,430 Listeners

30,609 Listeners

43,687 Listeners

38,950 Listeners

1,576 Listeners

484 Listeners

945 Listeners

12,704 Listeners

14,450 Listeners

12,130 Listeners

818 Listeners

1,542 Listeners

3,506 Listeners

2,800 Listeners

1,405 Listeners

9,556 Listeners

1,196 Listeners

5,569 Listeners

5,767 Listeners

421 Listeners

16,512 Listeners

6,592 Listeners

670 Listeners

2,821 Listeners

2,303 Listeners

644 Listeners

1,965 Listeners

82 Listeners

246 Listeners

20 Listeners