In this episode of ACM ByteCast, our special guest host Scott Hanselman (of The Hanselminutes Podcast) welcomes ACM Fellow Peter Lee, President of Microsoft Research. As leader of Microsoft Research, Peter incubates new research-powered products and lines of business in areas such as AI, computing foundations, health, and life sciences. Before Microsoft, he established a new technology office that created operational capabilities in ML, data science, and computational social science at DARPA, and before that he was head of the CS department at CMU. Peter served on President Obama’s Commission on Enhancing National Cybersecurity and has testified before both the US House Science and Technology Committee and the US Senate Commerce Committee. He coauthored the bestselling book The AI Revolution in Medicine: GPT-4 and Beyond. In 2024, he was named by Time magazine as one of the 100 most influential people in health and life sciences.

In the interview, Peter reflects on his 40+ years in computer science, from working on PDP-11s and Commodore Amigas to modern AI advancements. He highlights how modern technologies, built on decades of research, have become indispensable. He also talks about his healthcare journey, including work that earned him election to the National Academy of Medicine, and the potential (and limitations) of AI in medicine. Peter and Scott touch on the impact of LLMs, the lack of ethics education in traditional CS curricula, the challenges posed by growing AI complexity. Peter also highlights some important Microsoft Research work in AI for Science and Quantum Computing.

In this episode of ACM ByteCast, our special guest host Scott Hanselman (of The Hanselminutes Podcast) welcomes Mary Lou Jepsen, CEO and Founder of Openwater, a technical executive and inventor in the fields of display, imaging, and computer hardware with about 300 patents published or issued to her name. She founded and led two moonshots at Google X and was later an executive at Facebook/Oculus VR. Prior to this, she was a professor at the MIT Media Lab, where she co-founded and was the first CTO of One Laptop per Child (OLPC), and later founded Pixel Qi in Taipei, Taiwan, focused on the design and manufacture of displays. Jepsen has been named as one of the 100 most influential people in the world by Time Magazine (“Time 100”), CNN’s top “10 thinkers” in science and technology and has won numerous awards numerous from professional societies in the fields of optics, display, and electronics. She’s a frequent keynote speaker, has given two highly viewed TED talks, and is frequently featured in top global press publications.

In this episode of ACM ByteCast, Rashmi Mohan hosts Travis S. Humble, Director of the Quantum Science Center (QSC), a Distinguished Scientist at Oak Ridge National Laboratory, and Director of the lab’s Quantum Computing Institute. He leads the development of new quantum technologies and infrastructure to impact the DOE mission of scientific discovery through quantum computing. As director of the QSC, Travis leads the innovation of scalable, resilient quantum information technologies through new materials, devices, and algorithms and facilitates the transfer of quantum technologies to the broadest audience. He also holds a joint faculty appointment with the University of Tennessee Bredesen Center for Interdisciplinary Research and Graduate Education working with students on energy-efficient computing solutions. Travis is Editor-in-Chief for ACM Transactions on Quantum Computing, Associate Editor for Quantum Information Processing, and Co-Chair of the IEEE Quantum Initiative. 

Travis describes his journey into quantum computing, which began in theoretical chemistry, where he studied quantum processes in chemical reactions. He explains the difference between classical and quantum computing and why quantum computing is particularly well suited for scientific applications such as drug discovery and energy solutions. He talks about Oak Ridge’s quantum computing resources and how researchers can access them. Travis also stresses the role education in advancing quantum computing and shares his predictions for its near future.

In this episode of ACM ByteCast, Harald Störrle hosts Darja Smite, Professor of Software Engineering at Blekinge Institute of Technology and a part-time research scientist at SINTEF ICT. Darja is an expert on the future of work and the impact of globalization and offshoring in software companies. She has conducted research with and international companies such as ABB, Boss Media, CALVI, DXC, Emerson Process Management, Ericsson, SONY, Spotify, and, Telenor and has insights from cooperating with offshore vendors in India, China, Poland, Latvia, Ukraine and Russia.

In this episode, part of a special collaboration between ACM ByteCast and the American Medical Informatics Association (AMIA)’s For Your Informatics podcast, Sabrina Hsueh hosts accessibility researcher and inventor Chieko Asakawa, an IBM Fellow at the IBM T.J. Watson Research Center, the Chief Executive Director of The National Museum of Emerging Science and Innovation (Miraikan) in Japan, and an IBM Distinguished Service Professor at Carnegie Mellon University. Chieko’s inventions include the Home Page Reader (HPR); a word processor for Braille documents; a digital library for Braille documents; an application to improve accessibility of streaming services; and, most recently, the AI Suitcase project. Her career has been recognized with numerous prestigious awards and honors, including becoming the first Japanese woman IBM Fellow in 2009, receiving the “Medal of Honor with Purple Ribbon” from the Emperor of Japan in 2013, her induction into the US National Inventors Hall of Fame in 2019, being named a Fellow of the National Academy of Inventors, and the ACM SIGACCESS Award for Outstanding Contributions to Computing and Accessibility in 2024.

In this episode of ACM ByteCast, Rashmi Mohan hosts Alvin Wang Graylin, Global VP of Corporate Development at HTC. Alvin is also Chairman of the Virtual World Society, Vice-Chair of the Industry of VR Alliance, and President of the Virtual Reality Venture Capital Alliance. Alvin is a leader in the virtual and augmented reality industries. As a serial entrepreneur, he founded four venture-backed startups across sectors including AI-driven conversational search, mobile social networks, ad tech, and big data AI analytics, spanning both China and the U.S. As an active investor, he funded more than 100 startups and played a pivotal role in the establishment of HTC’s ViveX Global VR accelerator and SOSV’s mobile internet investment incubator. A frequent keynote speaker at leading international conferences, Alvin is regularly featured in major media outlets, where he provides thought leadership on immersive computing (AR/VR/MR), AI, entrepreneurship, venture investing, and the Chinese market. His latest book, Our Next Reality, examines how AI and XR convergence will reshape society. He holds an M.S. in CS specializing in AI from MIT, an M.S. in Business from MIT’s Sloan School of Management, and a B.S. in Electrical Engineering from the University of Washington, focusing on VR, AI, and CPU architecture.

In this episode of ACM ByteCast, Bruke Kifle hosts ACM Fellow and ACM Distinguished Service Award recipient Jennifer Chayes, Dean of the College of Computing, Data Science, and Society at UC Berkeley. Before joining Berkeley, she co-founded the Theory Group at Microsoft Research Redmond and later founded and led three interdisciplinary labs: Microsoft Research New England, New York City, and Montreal. Her research areas include phase transitions in CS, structural and dynamical properties of networks including graph algorithms, and applications of ML. Jennifer is one of the inventors of the field of graphons, widely used for the ML of large-scale networks. Her recent work includes generative AI and ML theory in areas like cancer, immunotherapy, climate change, and ethical decision making, with more than 150 scientific papers authored and 30 patents she co-invented. Her honors and recognitions include the Anita Borg Institute Women of Vision Leadership Award, SIAM’s John von Neumann Lecture Award (the highest honor bestowed by SIAM), and election to the American Academy of Arts and Sciences and the National Academy of Sciences. She serves on numerous boards and advisory committees and has served on the ACM A.M. Turing Award Selection Committee.

In this episode of ACM ByteCast, Bruke Kifle hosts ACM Fellow Roger Dannenberg, a Professor Emeritus of Computer Science, Art & Music at Carnegie Mellon University. Dannenberg is internationally renowned for his research in computer music, particularly in the areas of programming language design, real-time interactive systems, and AI music. Throughout his career, he has developed innovative technologies that have revolutionized the music industry and is known for creating Audacity, the widely known and used audio editor. In addition to his academic work, His other projects include Music Prodigy, aiming to help thousands of beginning musicians and Proxor, aiming to help software developers launch a successful career. Roger is also an accomplished musician and composer, having performed in prestigious venues around the world.

Roger traces his two lifelong passions for computer science and music, and his fascination with the connection between sound, mathematics, and physics. He describes the signal changes in interactive computer music, which once required specialized hardware but has since been replaced by ubiquitous software-based audio processing. Roger and Bruke discuss the promise of AI in music, especially for enhancing creativity and live performance, as well as the challenges of balancing AI with human labor and creativity. Roger also describes his work on the powerful open-source audio editor Audacity (co-developed with former student Dominic Mazzoni), which has democratized music production and is now used by millions of users worldwide. Finally, he talks about some recent projects in music analysis and composition, and reflects on his role as an academic and advisor. 

In this episode of ACM ByteCast, Bruke Kifle hosts ACM and IEEE Fellow Xin Luna Dong, Principal Scientist at Meta Reality Labs. She has significantly contributed to the development of knowledge graphs, a tool essential for organizing data into understandable relationships. Prior to joining Meta, Luna spent nearly a decade working on knowledge graphs at Amazon and Google. Before that, she spent another decade working on data integration and cleaning at AT&T Labs. She has been a leader in ML applications, working on intelligent personal assistants, search, recommendation, and personalization systems, including products such as Ray-Ban Meta. Her honors and recognitions include the VLDB Women in Database Research Award and the VLDB Early Career Research Contribution Award.

In this episode of ACM ByteCast, Rashmi Mohan hosts Nashlie Sephus, Principal Tech Evangelist for Amazon AI focusing on fairness and identifying biases at AWS AI. She formerly led the Amazon Visual Search team in Atlanta, which launched visual search for replacement parts on Amazon Shopping using technology developed at her former start-up Partpic (acquired by Amazon), where she was the CTO. She is also CEO of Bean Path, a nonprofit startup developing the Jackson Tech District, a planned community and business incubator in Jackson, Mississippi. Nashlie earned her PhD from the School of Electrical and Computer Engineering at the Georgia Institute of Technology, where her core research areas were digital signal processing, ML, and computer engineering. She has been featured in The Atlanta Journal-Constitution, CBS kids’ show Mission Unstoppable, Black Enterprise, Ebony, Amazon Science, AWS re:Invent, Afrotech, and Your First Million podcast, among others. She also serves on several start-up and academic advisory boards along with mentoring others and investing in Atlanta-based start-ups. Her honors and recognitions include the BEYA 2024 Black Engineer of the Year Award, Mississippi Top 50, 2019 Ada Lovelace Award, and Georgia Tech Top 40 Under 40.

Nashlie describes her early love for mathematics and music and how these informed her later doctoral research in digital signal processing in music data mining. She shares a personal experience that deeply influenced her work in AI, particularly in responsible AI and fairness, which eventually led her to her current role mitigating bias at Amazon, notably in facial recognition technologies. Nashlie and Rashmi discuss the importance of building diverse teams to practicing responsible AI and building sound products, as well as collaboration with open consortia and organizations such as the Algorithmic Justice League and Black in AI. Nashlie describes the inception and growth of Partpic, an app she started developing while finishing school. She also talks about BeanPath, her nonprofit organization with a mission to bridge the tech gap in Jackson, Mississippi through makerspaces, networking, and community engagement.