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Acute Gout Flare (Inpatient)
Visit pointofcaremedicine.com to see the templates, pearls, literature, and other resources discussed in this episode.
Our mission is to create accessible and easy-to-use digital resources that help healthcare professionals tackle common clinical presentations at the point of care, without getting bogged down by unnecessary details or trivia.
Time Stamps:
00:00:08 - Background and Definitions
00:01:39 - Pathophysiology
00:03:22 - Admission Checklist
00:04:25 - HPI Intake
00:05:51 - Physical Exam
00:06:06 - Differential Diagnosis
00:06:38 - Plan - Workup and Treatment
00:08:54 - If You Remember Nothing Else
00:10:14 - Pearls - Etiology
00:11:00 - Pearls - Presentation and Diagnosis
00:13:07 - Pearls - Treatment
00:15:20 - Literature and Trials
00:15:56 - Wrap Up
Show Notes:
Gout Review (NEJM, 2022)STOP Gout Trial (NEJM, 2022) - allopurinol non-inferior to febuxostat for preventing flares and for reaching target urate concentrations at 48 weeks
CARES Trial (NEJM, 2018) suggested an increased risk of mortality in febuxostat from cardiac events, but a follow-up FAST Trial (Lancet, 2020) showed no difference compared to allopurinol - FDA still has a black box warning
Calcium Pyrophosphate Deposition Disease (CPPD) Review (NEJM, 2016)
View all episodes
By RMO Medical Education
4.8
66 ratings
Visit pointofcaremedicine.com to see the templates, pearls, literature, and other resources discussed in this episode.
Our mission is to create accessible and easy-to-use digital resources that help healthcare professionals tackle common clinical presentations at the point of care, without getting bogged down by unnecessary details or trivia.
Time Stamps:
00:00:08 - Background and Definitions
00:01:39 - Pathophysiology
00:03:22 - Admission Checklist
00:04:25 - HPI Intake
00:05:51 - Physical Exam
00:06:06 - Differential Diagnosis
00:06:38 - Plan - Workup and Treatment
00:08:54 - If You Remember Nothing Else
00:10:14 - Pearls - Etiology
00:11:00 - Pearls - Presentation and Diagnosis
00:13:07 - Pearls - Treatment
00:15:20 - Literature and Trials
00:15:56 - Wrap Up
Show Notes:
Gout Review (NEJM, 2022)STOP Gout Trial (NEJM, 2022) - allopurinol non-inferior to febuxostat for preventing flares and for reaching target urate concentrations at 48 weeks
CARES Trial (NEJM, 2018) suggested an increased risk of mortality in febuxostat from cardiac events, but a follow-up FAST Trial (Lancet, 2020) showed no difference compared to allopurinol - FDA still has a black box warning
Calcium Pyrophosphate Deposition Disease (CPPD) Review (NEJM, 2016)
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