The Point of Care Podcast

Acute Gout Flare (Inpatient)


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Visit pointofcaremedicine.com to see the templates, pearls, literature, and other resources discussed in this episode.

Our mission is to create accessible and easy-to-use digital resources that help healthcare professionals tackle common clinical presentations at the point of care, without getting bogged down by unnecessary details or trivia.


Time Stamps:


00:00:08 - Background and Definitions

00:01:39 - Pathophysiology

00:03:22 - Admission Checklist

00:04:25 - HPI Intake

00:05:51 - Physical Exam

00:06:06 - Differential Diagnosis

00:06:38 - Plan - Workup and Treatment

00:08:54 - If You Remember Nothing Else

00:10:14 - Pearls - Etiology

00:11:00 - Pearls - Presentation and Diagnosis

00:13:07 - Pearls - Treatment

00:15:20 - Literature and Trials

00:15:56 - Wrap Up



Show Notes:

Gout Review (NEJM, 2022)STOP Gout Trial (NEJM, 2022) - allopurinol non-inferior to febuxostat for preventing flares and for reaching target urate concentrations at 48 weeks

CARES Trial (NEJM, 2018) suggested an increased risk of mortality in febuxostat from cardiac events, but a follow-up FAST Trial (Lancet, 2020) showed no difference compared to allopurinol - FDA still has a black box warning
Calcium Pyrophosphate Deposition Disease (CPPD) Review (NEJM, 2016)

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The Point of Care PodcastBy RMO Medical Education

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