Dr. Raymond Chung, a gastroenterologist and Transplant Hematologist who is the Director of the Hepatology and Liver Center at MGH and a Professor of Medicine at Harvard Medical School, discusses acute liver failure with Dr. Joyce Zhou, a RTL host and internal medicine resident. In the episode, he defines acute liver failure (ALF) and discusses pathophysiology, etiologies of ALF, complications by system, and tenets of management. He also discusses new treatments for liver failure in the developmental pipeline.