Please visit answersincme.com/860/27391-replay3 to participate, download slides and supporting materials, complete the post test, and obtain credit. In this activity, experts in breast cancer discuss patient-centered strategies to optimize quality of life by implementing a proactive approach to adverse event management for HR+, HER2- mBC. Upon completion of this activity, participants should be better able to: Outline evidence-based clinical strategies to enhance a sequential therapeutic approach in real-world patient populations; and Identify proactive, patient-focused strategies to elevate survivorship for patients receiving ADCs for HR+, HER2- mBC.