Dr. Anand Vaidya, an endocrinologist and the director of the Center for Adrenal Disorders at Brigham and Women's Hospital, discusses adrenal insufficiency with Dr. Navin Kumar (host) and Bina Kassamali (script writer and case presenter). They discuss the presentation of adrenal insufficiency (AI) and its triggers, a framework for primary vs. secondary causes of AI, an endocrine work-up for AI and related diseases, and the management of AI with steroids and patient education. Dr. Vaidya also makes a brief note on adrenal crises. The episode ends with some clinical pearls from both Bina and Dr. Vaidya.