Dr. Allison Feldt sits down with her own physician, Dr. Melissa Lange, ND of Honeybee Natural Medicine, for an unusually honest conversation about GLP medications. No sales pitch, no demonization just what the data says and what actually happened.Allison shares her own experience: 90 days on a GLP, at a dose below the standard therapeutic starting point, after already losing 100 pounds without one. She felt genuinely better. Sleep improved, anxiety dropped, digestion improved, and the constant mental load of food noise finally quieted. Then her DEXA scan came back showing 10 pounds of muscle lost over the year, despite training 5 days a week and eating 180 grams of protein daily.Dr. Lange brings the clinical picture. These drugs were developed as type 2 diabetes medications, and for that population the benefits are real and well documented. But in the wider weight loss population now being marketed to, clinical and post-trial data suggests up to 40 percent of the weight lost can be muscle mass. That matters enormously for the group these drugs are most heavily marketed to: perimenopausal and postmenopausal women, who are already losing estrogen’s protective effect on bone density. Less muscle means less force pulling on bone, which accelerates the path toward osteopenia and osteoporosis.They also cover why Dr. Lange would consider a GLP for less than 1 percent of her patients, why she requires quarterly labs and body composition scans for the ones she does prescribe to, the case for microdosing below every dose used in the research, the lowest effective dose principle and the patient whose cholesterol dropped 100 points on the smallest available statin, why these should function like training wheels rather than a permanent fixture, the real benefits showing up for endometriosis and PCOS, what the newer generations actually add, and the questions nobody can answer yet about telomeres, pancreatic function, and long term use.This is a conversation, not medical advice. Nothing here is a recommendation to start, stop, or change a medication. Talk to a physician who will actually monitor you.Dr. Melissa Lange, ND
Honeybee Natural Medicine, downtown Edmonds
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