A mysterious disease called acute flaccid myelitis (AFM) has been appearing in emergency rooms for about a decade. The disease has caused otherwise healthy children to lose the ability to move their arms and legs, and some become completely paralyzed. AFM is caused by a virus that's a cousin of the polio virus, earning it the nickname "the new polio.” Journalist and physician Eli Cahan joins Host Flora Lichtman to explain what doctors have been observing, the research efforts toward developing a vaccine, and what this emerging disease reveals about our readiness for future outbreaks and pandemics.

Read Cahan’s article about what fighting this “new polio” might look like as our healthcare infrastructure gets dismantled.

And, learning more about some non-cancerous cells may help researchers better understand how cancer progresses. When you think about how cancer spreads in the body, you’re probably thinking about cancer cells—they divide uncontrollably, form into tumors, and hide from the immune system. So, it makes sense that studying the behavior of these cells is critical to our understanding of cancer. But now, researchers are looking more closely at the non-cancerous cells that co-exist within tumors and the surrounding tissues. They make up what’s called the “colocateome.” Taking this more holistic approach to cancer research may help explain why some treatments don't work for all patients, and eventually may lead to more effective therapies. To better understand this expanding field, Host Ira Flatow talks with Sylvia Plevritis, a Stanford University cancer researcher. 

Correction: In the second story of this episode, with Dr. Sylvia Plevritis, we misspoke and said, “Some of the hardest to treat tumors are actually non-cancer cells.” This was in reference to tumors that are mostly non-cancer cells, not entirely non-cancer cells.

Guests:
Dr. Eli Cahan is a journalist and physician based in Boston, Massachusetts.
Dr. Sylvia Plevritis is a professor of biomedical data science and radiology at Stanford University.

Transcript is available on sciencefriday.com.

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