In a new book, author John Green traces how the disease has impacted culture, geography, and even fashion over the centuries.

Tuberculosis (TB) has had an incredibly large impact on human history. One staggering statistic? It’s been estimated that by the start of the 1800s, the disease had killed one in seven people who had ever lived. Because of this, tuberculosis affected human culture, geography, and fashion—and even killed off some of literature and media’s most famous heroines.

While TB incidence has gone down tremendously in the United States, it remains a massive issue in low-resource nations. About 1.25 million people die of TB each year, making it still the deadliest infectious disease in the world.

Author John Green explores humankind’s relationship with TB in the new book Everything is Tuberculosis: The History and Persistence of Our Deadliest Infection. Green speaks with Host Flora Lichtman about how TB’s path reflects our society and culture. He joins us from Indianapolis, Indiana.

Transcript for this segment will be available after the show airs on sciencefriday.com.

Subscribe to this podcast. Plus, to stay updated on all things science, sign up for Science Friday's newsletters.