Two marquee matchups are on the horizon in the Big Ten this Saturday, as No. 9 Oregon travels to Kinnick Stadium to take on No. 20 Iowa. Meanwhile, Big Noon Kickoff heads to Happy Valley, as Penn State hosts No. 2 Indiana.

Is there any shot that either underdog can keep it close? Can they even pull off the upset? Von Lozon and Kellen Voss discuss those two games and more on this week's Pick'em Podcast!

All odds courtesy of DraftKings Sportsbook. Please gamble responsibly.

Tulane at Memphis (-4.5)
Navy at No. 10 Notre Dame (-26.5)
LSU at No. 4 Alabama (-10)
No. 3 Texas A&M (-7) at No. 22 Missouri
No. 2 Indiana (-14.5) at Penn State
Wake Forest at No. 14 Virginia (-6.5)
No. 9 Oregon (-6.5) at No. 20 Iowa
No. 7 BYU at No. 8 Texas Tech (-10)

Learn more about your ad choices. Visit megaphone.fm/adchoices