Dr. Raji discusses the leading edge of quantitative neuroimaging volumetrics - the measurement of brain volumes from magnetic resonance images. Volume is a vital sign for the brain. When volumes are normal, this correlates to normal neuronal function. Reduction of brain volumes is seen with various neuropsychiatric disorders such as Alzheimer's disease, depression, and traumatic brain injury. What Dr. Raji's research has shown over the past 10 years is that brain volumes can actually change in relation to lifestyle choices from obesity to physical activity to dietary choices. This work has a tremendous impact on prevention of cognitive decline and preservation of brain health. His talk will overview these key points while presenting a framework for future growth of this new perspective in medicine. What Dr. Raji's research has shown over the past 10 years is that brain volumes can actually change in relation to lifestyle choices from obesity to physical activity to dietary choices.