Buffalo Bills aim to defend their AFC East dominance as they face a surging New England Patriots squad with everything on the line. Can Josh Allen lead the Bills past Drake May and a re-energized Patriots team determined to prove their Week 5 victory was no fluke? Nick Cattles and Joe Marino break down the pivotal storylines, including playoff implications, red zone efficiency, and whether Mike Vrabel’s hard-hitting messaging will rally New England in Foxborough.

Key matchups take center stage as the hosts spotlight the Bills’ rushing attack versus the Patriots’ struggling run defense, the chess match between Christian Barmore and Buffalo’s offensive line, and how each defense handles third-down pressure. Plus, they discuss the evolution of Drake Maye’s MVP campaign, critical injuries on both sides, and what each team must do to secure the division crown. Don’t miss this energetic, insight-packed preview of a season-defining AFC East showdown.

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