The exploding coronavirus pandemic is upending Thanksgiving traditions. But millions of Americans are determined to celebrate, hitting the road at a time when health officials want us to stay home. More than 2,200 COVID-related deaths were reported yesterday, the highest one-day toll in more than six months. But many of us are listening to those doctors' warnings, AAA predicts a 10% decline in Thanksgiving travel, the largest one-year drop since the 2008 recession. Michael Flynn's three-year legal fight is over, after President Trump pardoned him yesterday. The president's first National Security Adviser admitted to lying about his contacts with Russia. Argentina is in three days of national mourning for Diego Maradona, that country's greatest sports legend.

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There's been an alarming uptick in coronavirus cases, including more than 172,000 new ones yesterday. More than 2,100 people were reported dead in yesterday's 24-hour stretch, the most in a single day since early May. The pandemic has hit crisis levels in America's heartland. One hospital in Topeka, Kansas has had to turn a waiting area into hospital rooms for those without coronavirus because the ER is full. We could be getting closer to a coronavirus vaccine, with promising results from Pfizer and others. For more on the timeline, we're joined by Moncef Slaoui, who leads U.S. vaccine development for Operation Warp Speed. President-elect Joe Biden says his transition team is now in touch with officials across every federal agency. The next president revealed his secretary of state and other top diplomatic officials yesterday, and said he'll name members of his economic team next week.

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Dan Price and his company Gravity Payments, a credit card processing agency for small businesses, gained widespread attention in 2015 when Price announced to his 120 employees that the Seattle based company was instituting a minimum pay rate over three years of $70,000. Five years into the policy, Price spoke with CBS News correspondent Mola Lenghi about the effects the idea has had and some unintended consequences as well. Plus, Price discusses the impact the coronavirus pandemic has had on his business and other small businesses Gravity Payments serve.

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The U.S. government has determined that President-elect Joe Biden is the "apparent" winner of the election, which means the transition process can formally begin. President Trump tweeted that he made the approval "in the best interests of our country." But later, he tweeted he would never actually concede that he lost. The president-elect is wasting no time in shaping his new administration, announcing multiple names, especially in the area of national security. Top health experts are still pleading for Americans to stay home for Thanksgiving, while our country sets new and alarming COVID-19 records. The six hardest-hit states in hospitalizations are clustered in the Midwest. Some frontline workers in Florida say they can't wait for a vaccine.

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Moderna's president Dr. Stephen Hoge joins CBS News chief medical correspondent Dr. Jon LaPook to discuss the company's new coronavirus vaccine currently in clinical trials. Dr. Hoge shares what preliminary data is saying about the vaccine's effectiveness and what distribution of the vaccine will look like.

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As family and friends contemplate how to spend Thanksgiving together this year in the midst of the coronavirus pandemic, Dr. William Schaffner joins "CBS This Morning" national correspondent Jericka Duncan to offer advice on minimizing the virus of catching and spreading the virus. Dr. Schaffner, a professor of preventive medicine and infectious disease at Vanderbilt University also explains how there's a light at the end of the tunnel with the vaccines currently in development.

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Millions of Americans are going to extraordinary lengths to celebrate Thanksgiving, and many are waiting in lines for hours. People hope they will be safer with relatives if they test negative, but experts say it's not a sure thing. There are also massive lines for giveaways at food banks. And despite the pandemic, airports are still packed as millions take flights. Over the past three days, the U.S. reported more than 517,000 new cases. We're also getting some good news this morning about a potential vaccine from the pharmaceutical company AstraZeneca. In the 2020 election, Michigan and Pennsylvania could certify President-elect Joe Biden as the winner in those states today. President Trump's lawsuit to overturn the vote in Pennsylvania failed over the weekend. President-elect Biden plans to announce the first members of his cabinet tomorrow.

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More than 187,000 new coronavirus cases were reported yesterday, a new record. We're also seeing increased deaths, more than 2,000 people just yesterday. The coronavirus task force held its first public briefing yesterday in months. It came as the CDC issued a blunt new warning, telling Americans not to travel for Thanksgiving. We visit one small hospital in Rupert, Idaho which is in a desperate situation. Health and Human Services Secretary Alex Azar joins us to discuss the federal response. President-elect Biden said he discussed a nationwide mask mandate with governors, and insisted he does not intend to shut down the economy. President Trump's hopes of overturning vote totals in the election suffered a major setback in Georgia. Yesterday, Trump's personal lawyer, Rudy Giuliani, held an extraordinary news conference making unsubstantiated claims of fraud.

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Four-time Grammy winner Sam Smith is back with an emotional and uplifting third studio album, "Love Goes," which delves into Smith's mental health, heartbreak and journey to self-discovery and love. Smith tells Anthony Mason about learning to embrace their non-binary gender identity, facing ridicule and bullies, and the courage it took to come out.

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More than 250,000 people in the U.S. have now had their lives cut short due to the coronavirus. More than 19,000 have died this month alone, and daily cases are up 80% in just the last two weeks. The nation's largest public school system is going remote again, starting today. Despite the terrifying upward trend in coronavirus cases and deaths, many officials are still reluctant to take action that could save lives. The most recent testing shows AstraZeneca's vaccine developed at England's Oxford University works well, is safe, and is highly effective on older patients. It's been six days since President Trump made any public comments about the coronavirus, staying out of sight while he challenges the election results. President-elect Biden speaks with Democratic and Republican governors today in a virtual meeting to discuss the pandemic.

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