CFPCLearn

James and Mike celebrate their 500th, YIKES, podcast episode. You get to hear the entire intro song (Some People) written and recorded by Pete McCormack. We talk about the history of the podcast, thank a lot of people, and talk about the key messages and the philosophy we have tried to impart over the years. We then discuss a few cases that bring all these ideas into focus. THANKS SO MUCH FOR LISTENING and going on this journey with us. We have had a blast.

In episode 499, James and Mike invite Tina back again to discuss the evidence we have for dieting to lose weight and the impact of that on osteoarthritis knee pain. Overall, there isn’t a lot of evidence but some observational data suggests a benefit Unfortunately the relatively small weight loss achieved from most diets in RCTs did not demonstrate a difference on OA pain.

In episode 498, James and Mike invite Tina back yet again to talk about all the evidence we have for using compression stockings in patients with chronic lower limb edema. The NNT for recurrent cellulitis is pretty good (listen to find out the actual number) on the “NNT scale”.

In episode 497, James and Mike decide to go all in on the evidence around nutrition. We start out by going over how we try to actually figure out if a food is beneficial or harmful for you. And for nutrition is it ever tricky.

In episode 496, Mike and James continue the discussion with Ricky around the best available evidence we have for heart failure patients with preserved ejection fraction. Unfortunately, not much works but at least you’ll know the evidence.

In episode 495, Mike and James invite Ricky back again to talk about the options (not a lot) we have for heart failure patients with preserved ejection fraction. Ricky goes over all the trials and helps put them into context.

In episode 494, Mike and James invite Ricky Turgeon to talk about a potential new use for an old drug – colchicine. Ricky explains all the evidence we have for low-dose colchicine in people with a history of cardiovascular disease. We find out that colchicine reduces the risk of a cardiovascular event in a similar magnitude to statins – but will they be used as much as statins.? Find out what we think

In episode 493, Mike and James review all the Long COVID data. We talk about how many people get it, what the symptoms are and how long it can persist – and it can be a long time. COVID long-term is different than what we see with the regular flu.