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Maria Velkova, managing partner of Tabula Rasa Ventures, discusses the use of psychedelics in therapy and the work her organization is doing to support the space. She explains that psychedelic-assisted therapy is a novel care delivery model that combines traditional therapy with the use of psychedelic medicines. Velkova emphasizes the efficacy of these therapies, particularly for veterans who have high unmet needs. She also discusses the history of psychedelics and the negative connotations associated with them, as well as the current shift towards acceptance and understanding. The conversation explores the impact of psychedelics on the healthcare ecosystem and the potential for personalized, holistic, and disease-modifying approaches to mental health care. The conversation explores the role of money and investment in the psychedelic industry, the potential approval of MDMA-assisted therapy by the FDA, and the challenges and stigma surrounding psychedelic research and therapy. It emphasizes the need for capital to scale and provide broad patient access to innovative therapies.
As we await the FDA's decision on MDMA-assisted therapy, Maria shares promising Phase 3 trial results and discusses the broader applications of these treatments beyond veterans. Stay informed about the evolving landscape of psychedelic science, and gather valuable resources for further learning, including peer-reviewed journals and insightful platforms like Psychedelic Alpha and Double Blind. Maria also shares her top book recommendation, "The Myth of Normal" by Gabor Mate, and the impactful initiatives of Tabula Rasa and Energia, leaving us with a sense of hope and excitement for the future of mental health care.

Maria Velkova on LinkedIn

John R. Boyd's Conceptual Spiral was originally titled No Way Out. In his own words: 

“There is no way out unless we can eliminate the features just cited. Since we don’t know how to do this, we must continue the whirl of reorientation…”

March 25, 2025

Flow Learning Lab

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