Clinical Conversations

By NEJM Group

From NEJM Journal Watch, this podcast features lively interviews, concise summaries, and expert commentary that busy clinicians need to stay current and improve patient care.... more

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FAQs about Clinical Conversations:

How many episodes does Clinical Conversations have?

The podcast currently has 304 episodes available.

Clinical Conversations episodes:

August 21, 2009Podcast 54: A conversation with Aaron Caughey, whose analysis of the literature shows that elective induction of labor does not, contrary to dogma, in...
Well, the headline says it all. UCSF’s Aaron Caughey has just published a meta-analysis in Annals of Internal Medicine that shatters the dogma of elective induction’s being associated with cesarean delivery. I hope you’ll enjoy the conversation.
There won’t be a Clinical Conversation next week — I’m taking a week off — but the chit-chat returns in two weeks.
Older conversations are all archived here at podcasts.jwatch.org, and you can leave me a note at 1-617-440-4374 or at [email protected].
This week’s links:
Supervised Heroin Treatment Outperforms Methadone in Refractory Users
FDA Approves Hiberix as Haemophilus Vaccine Booster Dose
HPV Vaccine About as Safe as Other Vaccines, Researchers Report
Chinese Herb Appears Better Than Standard Treatment for Rheumatoid Arthritis
The Interview’s story link:
Elective Labor Induction Associated with Lower Cesarean Delivery Rates
The post Podcast 54: A conversation with Aaron Caughey, whose analysis of the literature shows that elective induction of labor does not, contrary to dogma, increase the risk of cesarean delivery. first appeared on Clinical Conversations.
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22min
August 14, 2009Podcast 53: Patients extubated with hypercapnia can be managed better with noninvasive ventilation, a new study shows.
Dr. Miquel Ferrer of the University of Barcelona took some time away from his holiday to talk with us about an article he’s just published in Lancet. His research shows that in a subgroup of patients with chronic respiratory diseases (mostly COPD) who are undergoing extubation but who remain in hypercapnia, noninvasive ventilation support is the way to go.
This week’s links:
Aspirin Use After Colorectal Cancer Diagnosis Linked to Lower Mortality Risk
H1N1 Update: CDC Issues Guidance for School Districts for Upcoming Academic Year
Using Noninvasive Ventilation after Extubation Associated with Better Outcomes in Some Patients with Chronic Respiratory Disease
The post Podcast 53: Patients extubated with hypercapnia can be managed better with noninvasive ventilation, a new study shows. first appeared on Clinical Conversations.
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14min
August 09, 2009Podcast 52: Screening for intimate-partner violence doesn’t seem productive or very protective. What’s a concerned clinician to do?
We talk with two authors of a JAMA study that indicates that such screening doesn’t accomplish the ultimate goal: protecting the patient from further abuse. Our guests have some advice.
This week’s news links:
Vertebroplasty No Better Than Sham Procedure in Osteoporotic Fractures
Researchers Advise Labor Induction for Women with Mild Hypertensive Disease Late in Pregnancy
TNF-Blockers to Carry New Cancer Warnings
Interview links:
JAMA article
Physician’s First Watch summary
BMJ review article mentioned in the interview
The post Podcast 52: Screening for intimate-partner violence doesn’t seem productive or very protective. What’s a concerned clinician to do? first appeared on Clinical Conversations.
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22min
July 31, 2009Podcast 51: In pregnant women with suspected H1N1, treat promptly! A conversation with Denise Jamieson of the CDC.
It’s simple: pregnant women (for un-simple reasons) are at greater risk for flu complications. It’s true even among hitherto apparently healthy patients. We’ve got a conversation with a CDC researcher who’s just published a paper in Lancet that urges prompt treatment, even in the face of pending lab results, with antivirals. Contact us at 1-617-440-4374.
This week’s links:
ACIP Recommends Five Groups as Priority Targets for H1N1 Vaccination
In Pregnancy, Treat Suspected H1N1 Promptly Without Awaiting Test Results
CDC “Full-Out” Recommends Seasonal Flu Vaccination for Children Over 6 Months
Expensive Tests to Evaluate Syncope Don’t Yield as Much as Simple Postural BP
ACOG Revises Labor Induction Guidelines
The post Podcast 51: In pregnant women with suspected H1N1, treat promptly! A conversation with Denise Jamieson of the CDC. first appeared on Clinical Conversations.
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10min
July 19, 2009Podcast 50: A re-podcast of an interview from February regarding the FDA’s plans for tightening regulations on opioid use.
This week the FDA approved a form of fentanyl that can be administered through the buccal mucosa — but its label carries boxed warnings. And two weeks ago, the opioid propoxyphene got boxed warnings on its Darvon and Darvocet formulations. The FDA is trying to regulate the opioids more closely, reminding prescribers and users of the dangers they pose. In February, after another FDA announcement on opioid control, we interviewed Dr. Roger Chou of Oregon Health Sciences University on this topic.
Since it’s summer and the news is relatively scant, I’m reprising the interview and skipping the news summary.
Enough said!
This week’s links:
Darvon, Darvocet to Get Stronger Warnings on Fatal Overdose Risk
FDA Approves Fentanyl Buccal Soluble Film
Older links:
FDA to Tighten Opioid Restrictions
Guidelines on Opioids in Noncancer Pain Issued
The post Podcast 50: A re-podcast of an interview from February regarding the FDA’s plans for tightening regulations on opioid use. first appeared on Clinical Conversations.
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12min
July 11, 2009Podcast 49: Three RASS Study researchers discuss their findings on the lack of benefit of renin-angiotensin blockade in the primary prevention of diab...
We talk with Drs. Michael Mauer, Ronald Klein, and Bernard Zinman about their paper in the July 2 New England Journal of Medicine reporting on the RASS study (Renin-Angiotensin System Study). They found that blockade of the renin-angiotensin system was not effective in the primary prevention of diabetic nephropathy in Type 1 diabetes.
This week’s news links:
Darvon, Darvocet to Get Stronger Warnings on Fatal Overdose Risk
Famotidine Associated with Fewer GI Complications from Low-Dose Aspirin
Dronedarone Approved for Maintenance Therapy in Atrial Fibrillation and Atrial Flutter
The week’s interview links:
Renal and Retinal Effects of Enalapril and Losartan in Type 1 Diabetes
The post Podcast 49: Three RASS Study researchers discuss their findings on the lack of benefit of renin-angiotensin blockade in the primary prevention of diabetic nephropathy in Type 1 diabetes. first appeared on Clinical Conversations.
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19min
July 02, 2009Podcast 48: A conversation with Les Irwig, which your bone scanner won’t like to hear.
Scanning patients on bisphosphonates within the first 3 years of therapy is just wasted effort, and may even be misleading clinically. That’s what researchers conclude after reanalysis of FIT trial data on some 6500 women taking either alendronate or placebo. Prof. Les Irwig of the University of Sydney talks about his team’s findings and what they mean for clinicians used to doing densitometric studies to reassure patients about the progress of their therapy.
This week’s news links:
Diabetic Retinopathy, But Not Nephropathy, Benefits from Renin-Angiotensin Blockade
FDA Panel Votes to Ban Vicodin, Percocet
Value of CRP and Other Cardiovascular-Risk Biomarkers Questioned
Insulin Glargine Associated with Cancer Risk; ADA Calls Findings “Conflicting and Confusing”
This week’s Interview links:
Bone-Density Monitoring After Starting Bisphosphonates ‘Cannot Be Justified’
BMJ article
The post Podcast 48: A conversation with Les Irwig, which your bone scanner won’t like to hear. first appeared on Clinical Conversations.
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14min
June 29, 2009Podcast 47: Total knee arthroplasty’s cost-effectiveness — a conversation with Elena Losina
Who knew that discussing QALYs could be so enjoyable? Dr. Elena Losina guides the interviewer through the thicket of cost-effectiveness and points to resources that keep track of the cost-effectiveness of most procedures. This is all done in the context of discussing her paper in Archives of Internal Medicine on total knee arthroplasty.
This week’s links:
Offer High School Students HIV Testing, CDC Reiterates
Fibrinolysis for STEMI Should Be Followed by Transfer and PCI
Bone-Density Monitoring After Starting Bisphosphonates ‘Cannot Be Justified’
Providers Often Fail to Inform Patients of Abnormal Test Results
Interview links:
Total Knee Replacement Found Cost-Effective Across Risk Categories
Peter Neumann’s registry of cost-effectiveness studies
World Health Organization site on cost-effectiveness
The post Podcast 47: Total knee arthroplasty’s cost-effectiveness — a conversation with Elena Losina first appeared on Clinical Conversations.
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21min
June 19, 2009Podcast 46: Does Genetic Testing for Clotting Mutations Matter? An interview with Jodi Segal of Johns Hopkins
You’d think that a widely-ordered test would play a part in management and outcome, but two clotting mutations seem exceptions to that rule. Although often requested, the FDA-approved tests for Factor V Leiden and G20210A mutations don’t seem to figure greatly in case management of venous thromboembolism, at least according to the published literature. Dr. Jodi Segal and her team published a meta-analysis in JAMA this week, and she’s here to discuss the results.
This week’s links:
News–
CDC Counsels Infection-Control Vigilance to Prevent H1N1 in Health Workers
Zicam Nasal Cold Remedies Linked to Loss of Sense of Smell
Stents Not Associated with Improved Function in Renal Artery Stenosis
Leukotriene Modifiers for Asthma Associated with Neuropsychiatric Adverse Events
Interview links–
Does Testing for Clotting Mutations Improve Outcomes in VTE?
Agency for Healthcare Research and Quality (AHRQ)
The post Podcast 46: Does Genetic Testing for Clotting Mutations Matter? An interview with Jodi Segal of Johns Hopkins first appeared on Clinical Conversations.
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11min
May 29, 2009Podcast 45: Prof. Martin Dennis discusses new findings discouraging the use of compression stockings after stroke
Compression stockings, widely used to prevent DVT in patients after stroke, don’t work, according to new research published in Lancet. We’ve got the principal investigator, Martin Dennis of the University of Edinburgh, to talk with about this.
For your part, if you have someone you’d enjoy hearing talk about a bit of research or anything else bordering on the medical, let me know at 1-617-440-4374 or drop me a note at [email protected].
This week’s links:
Pressure Stockings ‘Should Not Be Used’ to Prevent DVT After Stroke, Lancet Commentators Say
Weighing the Benefits and Risks of Aspirin for Primary Prevention of Vascular Disease
Radiofrequency Ablation Eliminates Metaplasia in Dysplastic Barrett Esophagus
Tolvaptan Approved for Use in Hyponatremia
The post Podcast 45: Prof. Martin Dennis discusses new findings discouraging the use of compression stockings after stroke first appeared on Clinical Conversations.
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13min

FAQs about Clinical Conversations:

How many episodes does Clinical Conversations have?

The podcast currently has 304 episodes available.