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A spike in feline H5N1 cases has many of us asking the same question: how did bird flu end up in our living rooms? We sit down with author and clinician Dr. Jane Sykes to map the path from migratory birds to household pets, spotlighting the two biggest drivers of risk for cats—predation on infected wildlife and contaminated raw diets. The conversation is candid, practical, and rooted in current data, with clear guidance for veterinarians and pet owners who want to reduce danger without fear or hype.

We break down the clinical pattern that should trigger suspicion: a rapidly worsening illness with fever, lower respiratory signs, neurologic changes like ataxia or seizures, hypersalivation, and even sudden vision loss. Jane shares a step-by-step plan for what to do next: preserve the suspect diet for testing, notify local public health partners, and coordinate diagnostics through NAHLN labs with NVSL confirmation. We also unpack why household cases typically arise from common exposure rather than cat-to-cat spread, and why ending raw feeding across the home is the first and most effective intervention. The oseltamivir question comes up too; Jane weighs the risks, pharmacologic unknowns, and stewardship concerns around antivirals in cats.

Listeners get concise takeaways: cooked diets are safer, indoor life or secure catios cut exposure, and detailed dietary histories matter more than ever because many raw products look like pasteurized foods. We touch on the evolving clade 2.3.4.4b, the possibility of reassortment in cats, and why dogs appear more resistant yet still susceptible to infection. Jane points to the research we still need—serology to find silent infections, better food-chain surveillance, and communication tools that help us talk about diet without blame. Subscribe, share with a colleague or pet-loving friend, and leave a quick review to help more people find evidence-based guidance on companion animal health.

JAVMA article: https://doi.org/10.2460/javma.25.06.0388

Washington Post article: https://wapo.st/49isM8M

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