In the summer of 1921, 39-year-old Franklin Delano Roosevelt was on vacation with his family when he developed a fever, muscle aches, and chills. Pain spread to his legs, and soon, he was paralyzed from the waist down. Doctors diagnosed him with polio, which was fast becoming America’s most dreaded infectious disease.

Every summer, polio struck without warning, causing swimming pools and movie theaters to close and panicked parents to keep their children indoors. Polio killed thousands of Americans each year and paralyzed many more. But scientists had no idea how to stop it.

Roosevelt and his friend and colleague Basil O’Connor resolved to change that, launching the March of Dimes, a revolutionary fundraising campaign that galvanized millions of Americans to donate their time and money to the fight against polio.

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