In this episode, some of the world’s leading intensivists from low-and middle-income countries discuss the special challenges that they have faced on the COVID-19 front lines, talk about what their countries are doing to combat the disease, and explore the impact of COVID-19 on their flu season as they are emerging from winter into spring. (Originally recorded November 5, 2020) Moderators: Steven Q. Simpson, MD, FCCP, and Alice Gallo De Moraes, MD. Panelists: Sai Praveen Haranath, MBBS, MPH, FCCP; Flavia Machado, MD; and Mervyn Mer, MBBCh, PhD, FCCP. For more tools to help in the fight against COVID-19, visit CHEST’s COVID-19 Resource Center at chestnet.org/COVID19. **This program was made possible by an independent grant from Boehringer Ingelheim Pharmaceuticals, Inc., who provided financial support for the program.**