It has now been a year since the first vaccines against COVID-19 have become available, providing the world with our best defense against the pandemic. In this session, our expert panelists review the current state of the science on vaccines, variants, boosters, and emerging strategies to protect our most vulnerable patients. Additionally, they address strategies to reduce vaccine hesitancy in our patients and other health care workers. (Originally recorded December 2, 2021) Moderator: Ryan Maves, MD, FCCP. Panelists: Susan Kline, MD, and Joseph Khabbaza, MD. For more tools to help in the fight against COVID-19, visit CHEST’s COVID-19 Resource Center at chestnet.org/COVID19.