The University of Illinois is pulling the plug on its Discovery Partners Institute at The 78. Crain’s reporters Danny Ecker and John Pletz discuss with host Amy Guth.

Plus: United ignites surge in airline stocks, JB and MK Pritzker gave $5.6 million to put on DNC, feds begin airlifting Baxter medical supplies to curb shortage and Chicago-area grocery stores now have DMV kiosks.

City Hall may have disqualified itself from getting millions in federal housing dollars. Crain’s residential real estate reporter Dennis Rodkin joins host Amy Guth news to discuss that and other news from the market.

Plus: Abbott Labs board OKs $7 billion stock buyback program, United rebounds from price-cut pressure and authorizes $1.5 billion share buyback, Boeing judge seeks more information before plea deal ruling and after three slow years, dealmakers expect to see plenty of M&A action in 2025.

Crain’s health care reporters Katherine Davis and Jon Asplund talk with host Amy Guth about how Chicago-area hospitals are coping with dwindling supply levels of IV fluid after Hurricane Helene halted production at a North Carolina Baxter plant.

Plus: Walgreens is closing stores and bleeding cash, but new CEO insists it's hitting long-term marks; Blue Cross antitrust lawsuit reaches $2.8B tentative settlement; True Value files for bankruptcy to sell itself to rival Do It Best; and Adams Street raises $1.2 billion for venture investments.

The members-only Astor Club now touts its own Michelin-starred chef. Crain's restaurants reporter Ally Marotti discusses the reimagining of the former Maxim’s space with host Amy Guth.

Plus: Boeing to cut workforce by 10% as strike eats into reserves, former Loretto CEO indicted on corruption and embezzlement charges, distressed Rosemont office complex hits the market and Chicago Fed chief praises progress on inflation and labor market.

Crain’s politics reporter Justin Laurence talks with host Amy Guth on Pedro Martinez, who's locked in a power struggle with Mayor Brandon Johnson, and his strategy banking on a TIF surplus to balance the CPS budget, which has drawn skepticism from the City Council.

Plus: Pritzker calls on Stellantis to get moving on Belvidere reopening, Chicago hospitals cope with dwindling supply of IV fluid, JLL unit cashes out of West Loop apartments for $76 million, Don Wilson's crypto unit hit with SEC charges over $2 billion in trades and United adding international flights as leisure travel demand grows.

Crain’s residential real estate reporter Dennis Rodkin joins host Amy Guth to talk news from the local market, including a new look for a famous cottage that endured the Great Chicago Fire, Harold Washington’s childhood home going up for sale and two suburbs where the record home price just went up.

Plus: Mayor Johnson asks department heads to model layoff scenarios in bid to close the city’s budget gap; Lurie ranked No. 1 pediatric hospital in Illinois, among top 10 in the U.S.; lender looks to unload distressed Rolling Meadows office complex; and President Biden announces plan to fast-track lead pipe replacement in the U.S.

Crain’s health care reporter Katherine Davis joins host Amy Guth to talk about the medical device subsidiary of a Japanese company expanding its operations here with a $20 million commitment and promise to hire 100 more workers.

Plus: City Council members push back as Johnson appoints new CPS board, McDonald's alleges major beef companies fixed prices in new lawsuit, Shore Capital raises $1.9 billion for three investment funds and a Rivian misstep triggered the parts shortage that's hobbling its EV output.

Plans for the quantum campus in South Chicago reveal a site more than four times bigger than Lincoln Yards. Crain’s commercial real estate reporter Danny Ecker talks with host Amy Guth about the site and its potential impact.

Plus: Chicago Mayor Brandon Johnson unveils picks to replace school board after mass resignation, Rivian seeking federal loan to restart Georgia EV plant project, Stellantis sues UAW to stop strike over plant investments and Walgreens to pay $80 million in Baltimore opioid settlement.

Crain's health care reporter Katherine Davis talks with host Amy Guth about the owner of a Chicago COVID testing lab’s guilty plea over a $14 million fraud scheme and the biotech startup out of Northwestern that just landed new funding.

Plus: Pritzker leading trade mission to Japan, Metra considers expanding service from Union Station to O'Hare, Walgreens to launch student loan 401(k) match program and a Harry Potter concept and Spanish fashion chain coming to the Mag Mile.