The immune system naturally defends and repairs but when there is an immune burden then defense takes a back seat - "repair deficit" or inflammation, acute or chronic sets in. This is a well-recognized cause/amplifier of chronic, degenerative, and autoimmune conditions. When defense takes precedence over repair in the immune system, increased intestinal permeability intensifies the defense work in the immune system. Partially broken-down food remnants get through impaired intestinal walls and set the stage for host hospitality to chronic infection and/or autoimmune, chronic degenerative illness. Delayed or late-phase food and other chemical sensitivities can also contribute to chronic low-grade systemic inflammation. With the world coming out of a COVID stricken few years, we need to devote additional emphasis on the state of the immune system. There is so much information that has been disseminated about this that it is time to make sense of it all. Knowing which cells to look at and which high sensitive tests to look at, is vital and can make a difference. Adequate personalized intake of protective antioxidants and nutrients, guided lifestyle modifications and actions that target improved acid alkaline balance ( Nature's pHarmacy) further allows the innate immune system to flourish, fight the inflammatory state and restore repair, providing relief from "repair deficit". - our main focus in helping folks thrive in the 21st Century !