Denis Noble is a renowned British biologist and pioneer in systems biology, known for his groundbreaking work on the heart and his influential contributions to the understanding of biological systems.

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Timestamps:

00:00 - Intro

00:20 - Neo-Darwinism is Dead

06:30 - Richard Dawkins Differences

17:02 - Purpose As Individual Agents / Purpose Given

26:05 - Function vs. Purpose in Living Systems

33:30 - Gaia Hypothesis (Lovelock)

37:46 - Anti-Natalist

41:52 - “The Only Free Will Worth Having”

46:52 - Stochasticity

52:50 - Rupert Sheldrake / Morphic Resonance

59:11 - Holism

01:06:32 - Dualism / Separate Laws for Separate Parts

01:18:01 - Multi-Cellularity Emerged Long Ago

01:34:00 - Maladaptive Evolution Happens All the Time

01:39:18 - Denis Noble & Richard Dawkins

01:45:27 - What is Purpose? (For Agents)

01:53:22 - Outro / Support TOE

LINKS:

- Richard Dawkins book: https://www.amazon.com/Selfish-Gene-Anniversary-Introduction/dp/0199291152

- Denis Noble’s book: https://www.amazon.com/Understanding-Living-Systems-Life/dp/1009277367

- Gerald Edelman’s book: https://www.amazon.com/Neural-Darwinism-Theory-Neuronal-Selection/dp/0465049346

- Denis Noble’s paper with Daniel Phillips: https://physoc.onlinelibrary.wiley.com/doi/epdf/10.1113/JP284420

- The Music of Life (Denis’ book): https://www.amazon.com/Music-Life-Biology-Beyond-Genes/dp/0199228361

- Dance to the Tune of Life (Denis’ book): https://www.amazon.com/Dance-Tune-Life-Biological-Relativity/dp/1107176247

- Denis’ Progress in Biophysics paper: http://www.voicesfromoxford.org/wp-content/uploads/2021/07/Shapiro-Noble-2021.pdf

- The Illusions of the Modern Synthesis (Denis’s paper): https://link.springer.com/article/10.1007/s12304-021-09405-3

- The Origin of Species (Charles Darwin’s book): https://www.amazon.com/Origin-Species-Charles-Darwin/dp/0517123207

- Dawkins/Noble debate (transcript): https://www.denisnoble.com/wp-content/uploads/2023/02/TranscriptReferences.pdf

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