Delerium is an acute mental disorder associated with fluctuating changes in cognition and attention and is likely a consequence of another medical condition. In this episode, Dr. Heather Torbic discusses the incidence and types of delirium, pathogenesis and patient-specific risk factors with Dr. Abhijit Duggal. Dr. Torbic also covers bedside tools for the diagnosis of delirium and treatment options, including nonpharmacologic interventions. She stresses the need to develop a better understanding of delirium pathophysiology and to implement strategies for the prevention of delirium.