In this podcast, I share the summary of a project I worked on almost 20 years, but is still relevant today.

A grant was awarded to the Cedar Rapids (IA) community to study anticoagulation management using Lean and Six Sigma. One of the key analysis performed in the project was a Gage Repeatability and Reproducibility (R&R) study. We wanted to determine if blood samples taken from a patient on warfarin have the same International Normalized Ratio (INR) results when analyzed in different labs (reproducibility) and when analyzed multiple times in the same lab (repeatability).

Results showed a statistically significant difference among labs. The therapeutic range for INR is typically 2.0 to 3.0, yet the data showed a difference in INR of 0.5 among labs on a small sample of 10 warfarin patients, almost 50 percent of the range.

By the way, this entire podcast was spoken by my AI voice created by Eleven Labs.

Links for this episode:

• AHRQ Grant Summary: https://www.ahrq.gov/downloads/pub/advances2/vol3/Advances-Hurley_55.pdf

• Eleven Labs (affiliate link): ⁠⁠https://try.elevenlabs.io/lp5v7zzfm8mz⁠⁠

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