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Syphilis cases have surged 42% in the US, making it critical for emergency physicians to recognize and treat this "great masquerader." In this episode, hosts Sam Ashoo and Dr. T.R. Eckler break down the January 2026 Emergency Medicine Practice article on syphilis diagnosis and management. They cover the rising prevalence in high-risk populations, the four clinical stages (primary, secondary, latent, and tertiary), special presentations like neurosyphilis and congenital syphilis, and practical diagnostic approaches. With a national penicillin shortage, they discuss alternative treatment options including doxycycline and post-exposure prophylaxis. The conversation also addresses the dark history of the Tuskegee Study and its lasting impact on medical ethics. Whether you're seeing more cases in your ED or want to sharpen your diagnostic skills, this episode provides actionable insights for frontline providers.
Timestamps[0:00] Opening/Introduction
[0:11] Host Welcome & Resources
[0:50] Episode Introduction
[1:30] Epidemiology & Rising Cases
[4:30] Risk Factors & Screening
[6:30] Pathophysiology & Transmission
[9:30] Primary Syphilis
[12:30] Secondary Syphilis
[15:30] Tertiary & Latent Syphilis
[18:30] Neurosyphilis
[22:30] Congenital Syphilis
[25:30] Ocular & Otic Syphilis
[28:30] Differential Diagnosis & Pre-hospital Care
[31:30] History & Physical Examination
[34:30] Diagnostic Testing Overview
[38:30] Testing Details & Titers
[41:30] Treatment: Penicillin & Alternatives
[43:30] Closing
Subscribers, take the CME test here.Emergency Medicine Residents, get your free subscription by writing [email protected]In this episode, Sam Ashoo, MD and T.R. Eckler, MD discuss the December 2025 Emergency Medicine Practice article, Diagnosis and Management of Cannabis-Related Emergencies
Episode Outline:
Emergency Medicine Residents, get your free subscription by writing [email protected]
In this episode, Sam Ashoo, MD and Tim Horeczko, MD discuss the November 2025 Pediatric Emergency Medicine Practice article, Emergency Department Management of Measles, Mumps, Rubella, and Varicella in Pediatric Patients
00:00 Introduction to Emergency Medicine
00:21 Welcome and Holiday Greetings
01:16 Special Guest Introduction
01:41 Discussion on Pediatric Emergency Medicine
04:55 Epidemiology of Measles
08:16 Challenges in Diagnosing Measles
14:27 Mumps: Symptoms and Complications
27:36 Rubella: Risks and Symptoms
29:28 Varicella: Symptoms and Precautions
33:12 Differential Diagnosis and Conclusion
35:14 Using Inductive Reasoning in Medical Diagnosis
35:40 Recognizing Purpuric Rash and Its Implications
36:22 Guidance for EMS Colleagues on Handling Fever and Rash
37:14 Importance of Communication and Relationships with EMS
39:12 Decontamination and PPE Protocols for EMS
42:34 Detailed Patient Assessment in the ED
46:06 Diagnostic Testing and Clinical Diagnosis
49:20 Reporting Responsibilities and Treatment Protocols
01:01:19 Addressing Vaccine Controversies and Public Trust
01:06:25 Conclusion and Additional Resources
Check out Dr Horeczko's podcast - Pediatric Emergency Playbook
Emergency Medicine Residents, get your free subscription by writing [email protected]
In this episode, Sam Ashoo, MD and T.R. Eckler, MD discuss the November 2025 Emergency Medicine Practice article, Diagnosis and Management of Emergency Department Patients With Alcohol Withdrawal Syndrome
Emergency Medicine Residents, get your free subscription by writing [email protected]
In this episode, Sam Ashoo, MD and Lara Zibners, MD discuss the August 2025 Pediatric Emergency Medicine Practice article, Diphtheria, Pertussis, and Tetanus: An Update of Evidence-Based Management of Pediatric Patients in the Emergency Department
Check out Dr Zibner's podcast Unstable Vitals
Emergency Medicine Residents, get your free subscription by writing [email protected]
In this episode, Sam Ashoo, MD and T.R. Eckler, MD discuss the October 2025 Emergency Medicine Practice article, Emergency Department Evaluation and Management of Patients With Adrenal Insufficiency
Introduction
Article Overview
Clinical Context & Epidemiology
Pathophysiology
Differential Diagnosis
Prehospital Care
Emergency Department Evaluation
Physical Examination
Diagnostic Workup
Treatment
Special Populations
Common Pitfalls & Takeaways
ClosingSummary and final thoughts
Emergency Medicine Residents, get your free subscription by writing [email protected]
In this episode, Sam Ashoo, MD interviews Evan Dvorin, MD about the dangers of short term steroid use.
Background & Regional Differences
Inappropriate Steroid Use
Risks and Side Effects of Short-Term Steroid Use
Patient Communication & Shared Decision-Making
Impact of Provider Education & Quality Metrics
Special Populations & Scenarios
Medical-Legal Considerations
Alternatives & Symptom Management
Resources
Conclusion
Ochsner "Side effects from corticosteroids" Video: https://www.youtube.com/watch?v=PdMJ9HYxkck
In this episode, Sam Ashoo, MD and T.R. Eckler, MD discuss the September 2025 Emergency Medicine Practice article, Emergency Department Management of Patients With Status Epilepticus
Topic Introduction
Why Status Epilepticus Matters
Guidelines and Evidence
Classification and Diagnosis
Etiology and Workup
Prehospital and ED Management
Diagnostics
Treatment Approach
Special Populations
Risk Management Pitfalls
Clinical Pathway
Conclusion
Emergency Medicine Residents, get your free subscription by writing [email protected]
In this episode, Sam Ashoo, MD interviews Ali Chaudhary, MD about the benefits of working Locum Tenens in Emergency Medicine.
For more about Dr. Ali Chaudhary: https://thelocums.com/
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