Mohammad Dwidar, PhD, Assistant Staff in the Lerner Research Institute and Assistant Professor of Molecular Medicine at Cleveland Clinic Lerner College of Medicine, joins the Cancer Advances podcast to discuss the emerging role of engineered bacteria in cancer treatment. Listen as Dr. Dwidar explores the history of bacteria-based immunotherapy, strategies to enhance tumor specificity and safety, and how targeting tumor metabolites like kynurenine could open new therapeutic avenues across solid tumors.