Cleveland Clinic Cancer Advances

The Cancer Advances podcast is joined by Ofer Reizes, PhD, the Laura J. Fogarty Endowed Chair for Uterine Cancer Research, and Roberto Vargas, MD, Gynecologic Oncologist and Program Director for the Gynecologic Oncology Fellowship to discuss their research on targeting CD55 to combat chemoresistance in ovarian cancer patients. Listen as they insights into the mechanisms behind chemoresistance, the challenges it presents in treatment, and the potential for innovative therapies to transform patient outcomes.

Arun D. Singh, MD, Director of Ophthalmic Oncology at Cleveland Clinic Cole Eye Institute, returns to the Cancer Advances podcast to discuss iris melanoma. Listen as Dr. Singh talks about the unique characteristics of this rare eye cancer, the latest advancements in diagnosis and treatment, including cutting-edge imaging techniques and the potential of machine learning. Tune in for this insightful discussion on this rare type of melanoma.

The Cancer Advances podcast is joined by third-year internal medicine resident, Heya Batah, MD, and hematologist and medical oncologist, Moaath Khader Mustafa Ali, MD, MPH to discuss the latest findings on the combination of atezolizumab with carboplatin and etoposide in treating extensive stage small cell lung cancer. Listen as they talk about the real-world data presented by Dr. Batah at ASCO, focusing on the impact of atezolizumab on overall survival and progression-free survival compared to traditional chemotherapy alone.

Shlomo Koyfman, MD, Director of Head and Neck and Skin Radiation at Cleveland Clinic, joins the Cancer Advances podcast to talk about the latest ASCO clinical practice guidelines for managing osteoradionecrosis, a potential complication due to radiation therapy. Listen as Dr. Koyfman discuss how the new guidelines are designed to enhance the prevention, early detection, and management of osteoradionecrosis. He shares insights into how these guidelines can be put into practice, and the impact of these new strategies on patient care and survivorship.

Thach-Giao Truong, MD, Director of the Melanoma Program at Cleveland Clinic, joins the Cancer Advances podcast to discuss Tumor-Infiltrating Lymphocyte (TIL) therapy. This cutting-edge, personalized cancer treatment utilizes a patient's immune cells to target and destroy tumors.  Listen as Dr. Truong provides insights into the science behind TIL therapy, its advantages, and its potential to revolutionize treatment for patients with resistant melanoma and other challenging cancers.

Lily Wang, PhD, from the Department of Translational Hematology Oncology Research at Cleveland Clinic, joins the Cancer Advances Podcast to dive into her research on VISTA and LRIG1 interactions. Dr. Wang, an expert in immune mechanisms within cancer, discusses her lab's innovative work on these immune checkpoint proteins and their potential to overcome current treatment limitations. Discover how targeting the VISTA-LRIG1 axis could offer new strategies for tackling resistant tumors and improving patient outcomes.

Urologic Oncologist, Zeyad Schwen, MD, joins the Cancer Advances podcast to discuss prostate cancer and genomics. Learn about the latest advancements in genomic testing, its impact on diagnosis and treatment, and how these innovations shape personalized care in oncology. Dr. Schwen shares insights on the practical applications of genomics in prostate cancer, discusses ongoing research, and explores the potential future of cancer diagnostics.

Lukas Delasos, DO, Medical Oncologist at Cleveland Clinic, joins the Cancer Advances podcast to talk about the ADRIATRIC study. Dr. Delasos shares his insights on small cell lung cancer, detailing its aggressive nature, current treatment paradigms, and the promising results from the ADRIATIC study involving durvalumab as a consolidation therapy.

The Cancer Advances podcast is joined by Palliative Medicine physicians, Renato Samala, MD and Chirag Patel, MD to discuss the use of scrambler technology to treat neuropathic symptoms in cancer patients. Traditional medications for neuropathic symptoms caused by cancer treatments can be ineffective and often have side effects. Scrambler technology, which uses electrical signals to reprogram nerve signals, offers an innovative alternative. Listen as Dr. Samala and Dr. Patel explain the potential benefits of scrambler therapy, its application, patient selection, and prospects for better access and research on long-term outcomes.

Joel Cardenas Goicoechea, MD, MBA, a Gynecologic Oncologist at Cleveland Clinic Weston Hospital in Florida, joins the Cancer Advances podcast to discuss the benefits of robotic cytoreductive surgery combined with laparoscopic HIPEC for ovarian cancer. Listen as Dr. Cardenas explains how this innovative approach offers lower complication risks, reduced blood loss, and shorter hospital stays than traditional open surgery. Tune in to learn how these advancements enhance patient outcomes and quality of life in the treatment of ovarian cancer.