GLP-1 drugs like Ozempic, Wegovy, and Mounjaro have opened doors for people to lose weight. Should everyone have the option to take it? Those arguing “yes” say obesity needs to be treated using every available tool, especially for people for whom diet, lifestyle changes, and exercise aren’t enough. Those arguing “no” are concerned about its side effects and the risks if people don’t take them as directed. Now we debate: should prescription weight loss drugs be available for all? 

Arguing Yes: David Allison, Obesity Researcher; Dean and Distinguished Professor at the Indiana University School of Public Health-Bloomington 

Arguing No: Stuart W. Flint, Associate Professor of the Psychology of Obesity at the University of Leeds 

Emmy award-winning journalist John Donvan moderates 

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In the 2024 election, the Democrats did not have messaging that resonated with men, some say and is part of the reason Kamala Harris lost. Could leaning into identity politics to engage men work for future elections? Those arguing “yes” say focusing on men-related issues could help the Dems reconnect with a demographic that feels left behind. Those arguing “no” say focusing on gender and identity politics divide voters rather than unite them. Now we debate: Could Identity Politics Help Democrats Engage Men? 

Arguing Yes: Jackson Katz, Educator, Author, and Co-Founder of the Young Men's Research Institute 

Arguing No: Thomas Chatterton Williams, Staff Writer at The Atlantic; Visiting Professor of Humanities at Bard College; Nonresident Fellow at the American Enterprise Institute 

Emmy award-winning journalist John Donvan moderates 

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The clock is ticking on TikTok. The popular video sharing app is facing a looming deadline of January 19th, when the law effectively banning it in the U.S. is set to go into effect. Unless, that is, the Supreme Court steps in to save it this week. While we wait, we revisit our 2023 debate that asked this prescient question: Should the U.S. Ban TikTok?  

Arguing Yes: Kori Schake, Senior Fellow and Director of Foreign and Defense Policy Studies at the American Enterprise Institute 

Arguing No: Milton Mueller, Professor at the Georgia Institute of Technology School of Public Policy; Founder and Director of the Internet Governance Project

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Iran is getting closer to developing its first nuclear weapon. With tensions rising in the Middle East, should the U.S. and its allies take a stand? Those calling to stop Iran now argue this is a “now or never” moment for the region. Those calling for tolerance say while it’s not ideal, it is manageable, and maintaining diplomacy should be the focus. Now we debate: Can America and Its Allies Tolerate A Nuclear Iran, or Is It Time to Stop Them Now? 

Arguing STOP NOW: Behnam Ben Taleblu, Senior Fellow at the Foundation for Defense of Democracies 

Arguing TOLERATE: Barbara Slavin, Distinguished Fellow at the Stimson Center 

Emmy award-winning journalist John Donvan moderates 

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Millions of people have credited Alcoholics Anonymous with helping them stay sober from alcohol, but is it the best path for everyone? Those who say “yes” argue it is easily accessible to all and that its structure through the 12-step program helps people succeed. Those who say “no” argue say the abstinence model doesn’t work for everyone and there may be better alternatives. Now we debate: Does AA Work?  

Arguing Yes: Dan Griffin, Expert on Alcoholics Anonymous; Author of "A Man's Way Through the Twelve Steps"

Arguing No: Adi Jaffe, Founder of IGNTD; Author of "The Abstinence Myth"

Nayeema Raza, Journalist and Co-Host of the Semafor Podcast "Mixed Signals", is the guest moderator.

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How long would you like to live, and could science and technology make it possible? 

Longevity science aims to extend our healthy years through advancements in CRISPR, cellular reprogramming, and drug development. While private companies and philanthropists invest heavily in these innovations, should the government be responsible for funding these efforts? Those who say yes to government funding say that longevity research could revolutionize public health, keep aging populations productive in the workforce, and reduce the economic burden of age-related illnesses. Those opposed to public funding of longevity science say that true life extension beyond a decade might be unachievable, and it will take years before results are measurable. They argue that when and if these advances become available, they may only be for a smaller, affluent population. They also argue that long-known behavior choices like good nutrition and sleep should be adopted by all now, instead of chasing uncertain longevity advancements. 

With this context, we debate the question: Could Longevity Science Extend Your Health Span By Decades? Should the Government Fund It?  

Arguing Yes: Peter Diamandis, Founder and Chairman of the XPRIZE Foundation; Announced the XPRIZE Healthspan Competiton; Author of "Longevity Guidebook" 

Arguing No: Ezekiel J. Emanuel, Bioethicist; Vice Provost for Global Initiatives at the University of Pennsylvania 

Emmy award-winning journalist John Donvan moderates 

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Happiness is a complex emotion and mental state that can be achieved through virtue or pleasure. But should it be for the good of the individual or society? Those in favor of virtue point to the Stoics and the Founding Fathers, saying you should strive for a life of moral virtue and rationality. Those in favor of pleasure say everyone should be able to experience it and define their sources of happiness. Now we debate: The Pursuit of Happiness: Virtue or Pleasure? 

Arguing Virtue: Jeffrey Rosen, CEO & President of the National Constitution Center; Author of “The Pursuit of Happiness: How Classical Writers on Virtue Inspired the Lives of the Founders and Defined America” 

Arguing Pleasure: Roger Crisp, Professor of Moral Philosophy at the University of Oxford; Uehiro Fellow and Tutor in Philosophy at St. Anne's College, Oxford 

Nayeema Raza, Journalist at New York Magazine and Vox, is the guest moderator. 

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Some scientific studies have shown evidence that psychedelic drugs, when used in controlled therapeutic settings, may help patients with their mental health — but should they be recommended by your doctor? Those advocating for psychedelic use argue that it could be a welcome relief for patients who don’t respond to traditional medicine. Those against its use argue we don’t yet understand their long-term effects. Now we debate: Psychedelics for Mental Health: Help or Hype? 

Arguing Help: Ismail Ali, Director of Policy and Advocacy at MAPS 

Arguing Hype: Kevin Sabet, President and CEO at the Foundation for Drug Policy Solutions 

Emmy award-winning journalist John Donvan moderates 

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From economic turbulence and the dilemmas posed by artificial intelligence to the big-picture challenges of our time, the pillars of money, truth, and power shape the complex global landscape. In partnership with the Future Investment Initiative (FII), join us as twelve of the world’s greatest thinkers debate: “Clash of the Titans: Three Grand Challenges Facing Humanity,” “What is Europe’s Economic Outlook?”, and “Will AI-Generated Entertainment Replace Human Creativity?” 

Emmy award-winning journalist John Donvan, Open to Debate CEO Clea Conner, and moderator and journalist Edie Lush moderate.

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Fast fashion has taken over the fashion industry, but is less expensive, trendy clothing really worth the purchase? Those who say to “stop” argue fast fashion harms the environment in many ways and exploits workers in countries with lax regulations. Those who say “keep shopping” argue it’s up to shoppers to choose, as fast fashion offers affordable options, supports jobs, and boosts local economies. Now we debate: Fast Fashion: Shop or Stop?

Arguing Stop: Kenneth Pucker, Former COO of Timberland; Professor at The Fletcher School at Tufts University  

Arguing Shop: Katherine Mangu-Ward, Editor-in-Chief at Reason 

Emmy award-winning journalist John Donvan moderates 

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